Chemical composition of essential oil from Kosterm and its effect on the susceptibility and biofilm activities of and .

Chemical composition of essential oil from Kosterm and its effect on the susceptibility and biofilm activities of and .

Zaini, Nur Nabilah Mohd;Salleh, Wan Mohd Nuzul Hakimi Wan;Arzmi, Mohd Hafiz;Salihu, Abubakar Siddiq;Ab Ghani, Nurunajah;
Natural product research 2023 pp. 1-6
50
zaini2023chemicalnatural

Abstract

The chemical composition of the essential oil of (Lauraceae) was investigated for the first time. The essential oil was obtained by hydrodistillation and fully characterised by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The antifungal activity of essential oil was tested against and using the broth microdilution assay, whereas the microbial biofilms were determined using a semi-quantitative static biofilm. A total of 28 components (99.6%) were successfully identified, which were characterised by β-eudesmol (14.6%), -α-bergamotene (11.0%), α-copaene (8.5%), dodecen-1-ol (8.5%), and ()-nerolidol (8.3%). The essential oil exhibited activity against and with MIC values of 250 and 500 µg/mL, respectively. The essential oil increased the biofilm of by 38.25%, however, decreased the biofilm of by 47.89% when treated with 500 µg/mL. Thus, the essential oil has a promising application in dentistry inhibition of the growth of and However, the antibiofilm activity of the essential oil is only applicable for cariogenic

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0x95644003c57E6F55A65596E3D9Eac6813e3566dA
Article ID:
277502
Unique Identifier:
10.1080/14786419.2023.2278164
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Scimatic Chain (ID: 481)
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