Alternative lengthening of telomeres in normal mammalian somatic cells
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Alternative lengthening of telomeres in normal mammalian somatic cells

Axel A. Neumann, Catherine M. Watson, Jane R. Noble, Hilda A. Pickett, Patrick P.L. Tam, Roger R. Reddel;Axel A. Neumann;Catherine M. Watson;Jane R. Noble;Hilda A. Pickett;Patrick P.L. Tam;Roger R. Reddel;
genes & development 2013 Vol. 27 pp. 18-
150
reddel2013genesalternative

Abstract

Some cancers use alternative lengthening of telomeres (ALT), a mechanism whereby new telomeric DNA is synthesized from a DNA template. To determine whether normal mammalian tissues have ALT activity, we generated a mouse strain containing a DNA tag in ...

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DOI:
10.1101/gad.205062.112
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC355328...

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