Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Clusters Based on Integrated Genomic Surveillance, Outbreak Analysis and Contact Tracing in an Urban Setting

Walker, Andreas; Houwaart, Torsten; Finzer, Patrick; Ehlkes, Lutz; Tyshaieva, Alona; Damagnez, Maximilian; Strelow, Daniel; Duplessis, Ashley; Nicolai, Jessica; Wienemann, Tobias; Tamayo, Teresa; Kohns Vasconcelos, Malte; Hülse, Lisanna; Hoffmann, Katrin; Lübke, Nadine; Hauka, Sandra; Andree, Marcel; Däumer, Martin P; Thielen, Alexander; Kolbe-Busch, Susanne; Göbels, Klaus; Zotz, Rainer; Pfeffer, Klaus; Timm, Jörg; Dilthey, Alexander T; German COVID-19 OMICS Initiative (DeCOI); Altmüller, Janine; Angelov, Angel; Aschenbrenner, Anna C; Bals, Robert; Bartholomäus, Alexander; Becker, Anke; Bezdan, Daniela; Bitzer, Michael; Blum, Helmut; Bonifacio, Ezio; Bork, Peer; Casadei, Nicolas; Clavel, Thomas; Colome-Tatche, Maria; De La Rosa Velázquez, Inti Alberto; Diefenbach, Andreas; Dilthey, Alexander; Fischer, Nicole; Förstner, Konrad; Franzenburg, Sören; Frick, Julia-Stefanie; Gabernet, Gisela; Gagneur, Julien; Ganzenmüller, Tina; Gauder, Marie; Goesmann, Alexander; Göpel, Siri; Grundhoff, Adam; Grundmann, Hajo; Hain, Torsten; Heimbach, André; Hummel, Michael; Iftner, Thomas; Iftner, Angelika; Janssen, Stefan; Kalinowski, Jörn; Kallies, René; Kehr, Birte; Keller, Andreas; Keppler, Oliver; Kim-Hellmuth, Sarah; Klein, Christoph; Knop, Michael; Kohlbacher, Oliver; Köhrer, Karl; Korbel, Jan; Kremsner, Peter G; Kühnert, Denise; Kurth, Ingo; Landthaler, Markus; Li, Yang; Ludwig, Kerstin; Makarewicz, Oliwia; Marz, Manja; McHardy, Alice; Mertes, Christian; Münchhoff, Maximilian; Nahnsen, Sven; Nöthen, Markus; Ntoumi, Francine; Nürnberg, Peter; Ohler, Uwe; Ossowski, Stephan; Overmann, Jörg; Peter, Silke; Pfeffer, Klaus; Poetsch, Anna R; Protzer, Ulrike; Pühler, Alfred; Rajewsky, Nikolaus; Ralser, Markus; Rieß, Olaf; Ripke, Stephan; Rocha, Ulisses; Rosenstiel, Philip; Saliba, Emmanuel; Sander, Leif Erik; Sawitzki, Birgit; Scheithauer, Simone; Schiffer, Philipp; Schmid-Burgk, Jonathan; Schneider, Wulf; Schulte, Eva-Christina; Schultze, Joachim; Sczyrba, Alexander; Sharaf, Mariam L; Singh, Yogesh; Sonnabend, Michael; Stegle, Oliver; Stoye, Jens; Theis, Fabian; Vehreschild, Janne; Velavan, Thirumalaisamy P; Vogel, Jörg; von Kleist, Max; Walker, Andreas; Walter, Jörn; Wieczorek, Dagmar; Winkler, Sylke; Ziebuhr, John

Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Clusters Based on Integrated Genomic Surveillance, Outbreak Analysis and Contact Tracing in an Urban Setting

Walker, Andreas;Houwaart, Torsten;Finzer, Patrick;Ehlkes, Lutz;Tyshaieva, Alona;Damagnez, Maximilian;Strelow, Daniel;Duplessis, Ashley;Nicolai, Jessica;Wienemann, Tobias;Tamayo, Teresa;Kohns Vasconcelos, Malte;Hülse, Lisanna;Hoffmann, Katrin;Lübke, Nadine;Hauka, Sandra;Andree, Marcel;Däumer, Martin P;Thielen, Alexander;Kolbe-Busch, Susanne;Göbels, Klaus;Zotz, Rainer;Pfeffer, Klaus;Timm, Jörg;Dilthey, Alexander T;German COVID-19 OMICS Initiative (DeCOI);Altmüller, Janine;Angelov, Angel;Aschenbrenner, Anna C;Bals, Robert;Bartholomäus, Alexander;Becker, Anke;Bezdan, Daniela;Bitzer, Michael;Blum, Helmut;Bonifacio, Ezio;Bork, Peer;Casadei, Nicolas;Clavel, Thomas;Colome-Tatche, Maria;De La Rosa Velázquez, Inti Alberto;Diefenbach, Andreas;Dilthey, Alexander;Fischer, Nicole;Förstner, Konrad;Franzenburg, Sören;Frick, Julia-Stefanie;Gabernet, Gisela;Gagneur, Julien;Ganzenmüller, Tina;Gauder, Marie;Goesmann, Alexander;Göpel, Siri;Grundhoff, Adam;Grundmann, Hajo;Hain, Torsten;Heimbach, André;Hummel, Michael;Iftner, Thomas;Iftner, Angelika;Janssen, Stefan;Kalinowski, Jörn;Kallies, René;Kehr, Birte;Keller, Andreas;Keppler, Oliver;Kim-Hellmuth, Sarah;Klein, Christoph;Knop, Michael;Kohlbacher, Oliver;Köhrer, Karl;Korbel, Jan;Kremsner, Peter G;Kühnert, Denise;Kurth, Ingo;Landthaler, Markus;Li, Yang;Ludwig, Kerstin;Makarewicz, Oliwia;Marz, Manja;McHardy, Alice;Mertes, Christian;Münchhoff, Maximilian;Nahnsen, Sven;Nöthen, Markus;Ntoumi, Francine;Nürnberg, Peter;Ohler, Uwe;Ossowski, Stephan;Overmann, Jörg;Peter, Silke;Pfeffer, Klaus;Poetsch, Anna R;Protzer, Ulrike;Pühler, Alfred;Rajewsky, Nikolaus;Ralser, Markus;Rieß, Olaf;Ripke, Stephan;Rocha, Ulisses;Rosenstiel, Philip;Saliba, Emmanuel;Sander, Leif Erik;Sawitzki, Birgit;Scheithauer, Simone;Schiffer, Philipp;Schmid-Burgk, Jonathan;Schneider, Wulf;Schulte, Eva-Christina;Schultze, Joachim;Sczyrba, Alexander;Sharaf, Mariam L;Singh, Yogesh;Sonnabend, Michael;Stegle, Oliver;Stoye, Jens;Theis, Fabian;Vehreschild, Janne;Velavan, Thirumalaisamy P;Vogel, Jörg;von Kleist, Max;Walker, Andreas;Walter, Jörn;Wieczorek, Dagmar;Winkler, Sylke;Ziebuhr, John;

clinical infectious diseases pp. -

182

andreasclinicalcharacterization

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Tracing of SARS-CoV-2 population transmission chains is still a major challenge. We present an integrated system of genomic surveillance and show it to be capab

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