Low pH induced shape changes and vesiculation of human erythrocytes
Abstract
Shape changes and vesiculation were induced in intact human erythrocytes by gradually decreasing pH in the cell suspension. A sequence of different shapes preceding vesiculation was documented, i.e. discocytes, stomatocytes, and stomatoacantocytes. The final state was characterized by spherical moth …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
in vitro techniques
microscopy
electron
scanning
m gros
hydrogen-ion concentration*
pmid:8899418
s vrhovec
b zeks
erythrocyte membrane / drug effects
erythrocyte membrane / physiology*
erythrocyte membrane / ultrastructure*
erythrocytes / cytology*
erythrocytes / physiology*
erythrocytes / ultrastructure
sodium chloride / pharmacology
sodium lactate / pharmacology
sucrose / pharmacology
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274436
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