Effect of testosterone on lipolysis in human pre-adipocytes from different fat depots
Abstract
Testosterone in physiological concentrations causes a depot-specific reduction of catecholamine-stimulated lipolysis in subcutaneous fat cells, probably due to reduced protein expression of beta(2)-adrenoceptors and hormone-sensitive lipase. This could be an important pathogenic factor underlying re …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
female
male
body mass index
Body Weight
Adipocytes / cytology
Adipocytes / drug effects
adipocytes / metabolism*
kinetics
testosterone / pharmacology*
lipolysis / drug effects*
adipose tissue / anatomy & histology
pmid:14752604
doi:10.1007/s00125-003-1324-0
a dicker
m rydén
p arner
adipose tissue / chemistry
bucladesine / pharmacology
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