Differential effects of p19Arf and p16Ink4a loss on senescence of murine bone marrow-derived preB cells and macrophages
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Differential effects of p19Arf and p16Ink4a loss on senescence of murine bone marrow-derived preB cells and macrophages

David H. Randle, Frederique Zindy, Charles J. Sherr, Martine F. Roussel;David H. Randle;Frederique Zindy;Charles J. Sherr;Martine F. Roussel;
Proceedings of the National Academy of Sciences of the United States of America 2001 Vol. 98 pp. 9654-
150
roussel2001proceedingsdifferential

Abstract

Establishment of cell lines from primary mouse embryo fibroblasts depends on loss of either the Arf tumor suppressor or its downstream target, the p53 transcription factor. Mouse p19[Arf] is encoded by the Ink4a-Arf locus, which also specifies a ...

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DOI:
10.1073/pnas.171217498
URL:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC55507/

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