Regulation of E2Fs and senescence by PML nuclear bodies
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Regulation of E2Fs and senescence by PML nuclear bodies

Mathieu Vernier, Véronique Bourdeau, Marie-France Gaumont-Leclerc, Olga Moiseeva, Virginie Bégin, Fred Saad, Anne-Marie Mes-Masson, Gerardo Ferbeyre;Mathieu Vernier;Véronique Bourdeau;Marie-France Gaumont-Leclerc;Olga Moiseeva;Virginie Bégin;Fred Saad;Anne-Marie Mes-Masson;Gerardo Ferbeyre;
genes & development 2011 Vol. 25 pp. 41-
47
ferbeyre2011genesregulation

Abstract

The tumor suppressor PML (promyelocytic leukemia protein) regulates cellular senescence and terminal differentiation, two processes that implicate a permanent exit from the cell cycle. Here, we show that the mechanism by which PML induces a permanent ...

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DOI:
10.1101/gad.1975111
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC301293...

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Ref Key: ferbeyre2011genesregulation
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