Cytochrome P450-Catalyzed Insertion of Carbenoids into N-H Bonds
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Cytochrome P450-Catalyzed Insertion of Carbenoids into N-H Bonds

Wang ZJ;Peck NE;Renata H;Arnold FH;;
Chemical science 2014 Vol. 5 pp. -
128
zj2014chemicalcytochrome

Abstract

Expanding nature's catalytic repertoire to include reactions important in synthetic chemistry will open new opportunities for 'green' chemistry and biosynthesis. We demonstrate enzyme-catalyzed insertion of carbenoids into N-H bonds. This type of bond disconnection, which has no counterpart in natur …

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National Center for Biotechnology Information NCBI NLM MEDLINE pubmed abstract nih national institutes of health national library of medicine frances h arnold pmid:24490022 pmc3906682 doi:10.1039/c3sc52535j z jane wang nicole e peck

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