A regulatory cytoplasmic poly(A) polymerase in Caenorhabditis elegans

A regulatory cytoplasmic poly(A) polymerase in Caenorhabditis elegans

Wang L;Eckmann CR;Kadyk LC;Wickens M;Kimble J;;
Nature 2002 Vol. 419 pp. -
256
l2002naturea

Abstract

Messenger RNA regulation is a critical mode of controlling gene expression. Regulation of mRNA stability and translation is linked to controls of poly(A) tail length. Poly(A) lengthening can stabilize and translationally activate mRNAs, whereas poly(A) removal can trigger degradation and translation …

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