A regulatory cytoplasmic poly(A) polymerase in Caenorhabditis elegans
Wang L;Eckmann CR;Kadyk LC;Wickens M;Kimble J;;
Nature2002Vol. 419pp. -
256
l2002naturea
Abstract
Messenger RNA regulation is a critical mode of controlling gene expression. Regulation of mRNA stability and translation is linked to controls of poly(A) tail length. Poly(A) lengthening can stabilize and translationally activate mRNAs, whereas poly(A) removal can trigger degradation and translation …