TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease

TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease

Zhao GN;Tian ZW;Tian T;Zhu ZP;Zhao WJ;Tian H;Cheng X;Hu FJ;Hu ML;Tian S;Ding T;Chen S;Ji YX;Zhang P;Zhang XJ;She ZG;Yuan Y;Chen W;Bai L;Li H;;
cell metabolism 2021 Vol. 33 pp. -
190
gn2021celltmbim1

Abstract

Obesity is characterized by the excessive accumulation of the white adipose tissue (WAT), but healthy expansion of WAT via adipocyte hyperplasia can offset the negative metabolic effects of obesity. Thus, identification of novel adipogenesis regulators that promote hyperplasia may lead to effective …

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