Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

Katsutomo Okamura, Akira Ishizuka, Haruhiko Siomi, Mikiko C. Siomi;Katsutomo Okamura;Akira Ishizuka;Haruhiko Siomi;Mikiko C. Siomi;
genes & development 2004 Vol. 18 pp. 1655-
126
siomi2004genesdistinct

Abstract

In mammalian cells, both microRNAs (miRNAs) and small interfering RNAs (siRNAs) are thought to be loaded into the same RNA-induced silencing complex (RISC), where they guide mRNA degradation or translation silencing depending on the complementarity of ...

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