Systemic administration of ghrelin induces Fos and Egr-1 proteins in the hypothalamic arcuate nucleus of fasted and fed rats
Abstract
Ghrelin, a recently identified endogenous ligand for the growth hormone secretagogue (GHS) receptor, induces growth hormone (GH) secretion following systemic administration. We sought to determine whether systemic administration of ghrelin activates cells in the hypothalamic arcuate nucleus by exami …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
male
Rats
peptides / administration & dosage
immunohistochemistry
wistar
food*
transcription factors / biosynthesis*
ghrelin
peptide hormones*
dna-binding proteins / biosynthesis*
growth hormone / metabolism
fasting*
pmid:11069119
doi:10.1046/j.1365-2826.2000.00584.x
a k hewson
s l dickson
arcuate nucleus of hypothalamus / drug effects*
arcuate nucleus of hypothalamus / metabolism
early growth response protein 1
immediate-early proteins*
oligopeptides / pharmacology
peptides / pharmacology*
proto-oncogene proteins c-fos / biosynthesis*
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272362
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