Class II MHC/peptide complexes are released from APC and are acquired by T cell responders during specific antigen recognition

Class II MHC/peptide complexes are released from APC and are acquired by T cell responders during specific antigen recognition

Patel DM;Arnold PY;White GA;Nardella JP;Mannie MD;;
Journal of immunology (Baltimore, Md. : 1950) 1999 Vol. 163 pp. -
280
dm1999journalclass

Abstract

T cell expression of class II MHC/peptide complexes may be important for maintenance of peripheral self-tolerance, but mechanisms underlying the genesis of class II MHC glycoproteins on T cells are not well resolved. T cell APC (T-APC) used herein were transformed IL-2-dependent clones that constitu …

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