Mesenchymal factor bone morphogenetic protein 4 restricts ductal budding and branching morphogenesis in the developing prostate
Abstract
The budding of the urogenital sinus epithelium into the surrounding mesenchyme signals the onset of prostate morphogenesis. The epithelial and mesenchymal factors that regulate ductal budding and the ensuing process of ductal growth and branching are not fully known. We provide evidence that bone mo …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
gene expression regulation
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
u.s. gov't
male
P.H.S.
Inbred BALB C
Base Sequence
Knockout
in vitro techniques
in situ hybridization
developmental
cell division / drug effects
dna primers / genetics
morphogenesis / genetics
heterozygote
bone morphogenetic proteins / physiology*
mutant strains
mesoderm / cytology
epithelial cells / drug effects
prostate / drug effects
bone morphogenetic protein 4
bone morphogenetic proteins / genetics
prostate / embryology*
pmid:11401393
doi:10.1006/dbio.2001.0187
m l lamm
c a podlasek
w bushman
bone morphogenetic proteins / pharmacology
morphogenesis / drug effects
morphogenesis / physiology
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272074
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