Hereditary Diffuse Gastric Cancer: Prophylactic Surgical Oncology Implications
Current Language EN
English English Türkçe Türkçe Español Español Português Português Pусский Pусский Filipino Filipino Tiếng Việt Tiếng Việt हिन्दी हिन्दी العربية العربية বাংলা বাংলা Deutsch Deutsch 中文 中文

Hereditary Diffuse Gastric Cancer: Prophylactic Surgical Oncology Implications

Henry T. Lynch,Edibaldo Silva,Debrah Wirtzfeld,Pamela Hebbard,Jane Lynch,David G. Huntsman;Henry T. Lynch;Edibaldo Silva;Debrah Wirtzfeld;Pamela Hebbard;Jane Lynch;David G. Huntsman;
surgical clinics of north america 2008 Vol. 88 pp. 759-778
148
huntsman2008surgicalhereditary

Abstract

Hereditary diffuse gastric cancer (HDGC) is an autosomal dominantly inherited syndrome attributed to mutations of the E-cadherin gene, CDH1. There is no proven effective screening for early HDGC, and symptomatic disease is almost universally fatal. The only available effective option for CDH1 carriers is prophylactic total gastrectomy, but the variable age of onset of HDGC and the reduced penetrance (about 70%) of the CDHI gene further complicate patients' decision making.

Keywords

oncology decision making gastric cancer hereditary penetrance cadherin hdgc diffuse gastric cdhi

Access

DOI:
10.1016/j.suc.2008.04.006
URL:
https://sciprofiles.com/publication/view/6715cd796...

Citation

ID: 271715
Ref Key: huntsman2008surgicalhereditary
Use this key to autocite in SciMatic or Thesis Manager

References

References

No Bibliography

Blockchain Verification

Account:
NFT Contract Address:
0x95644003c57E6F55A65596E3D9Eac6813e3566dA
Article ID:
271715
Unique Identifier:
10.1016/j.suc.2008.04.006
Network:
Scimatic Chain (ID: 481)
Blockchain Readiness Checklist
Authors
Abstract
Journal Name
Year
Title
5/5
Creates 1,000,000 NFT tokens for this article
Token Features:
  • ERC-1155 Standard NFT
  • 1 Million Supply per Article
  • Transferable via MetaMask
  • Permanent Blockchain Record
Blockchain QR Code
Scan with Saymatik Web3.0 Wallet
Gas fees required in SCI Coins
Buy SCI

Saymatik Web3.0 Wallet

Google Play
App Store