Key concepts and limitations of statistical methods for evaluating biomarkers of kidney disease

Key concepts and limitations of statistical methods for evaluating biomarkers of kidney disease

Parikh CR;Thiessen-Philbrook H;;
journal of the american society of nephrology : jasn 2014 Vol. 25 pp. -
304
cr2014journalkey

Abstract

Interest in developing and using novel markers of kidney injury is increasing. To maintain scientific rigour in these endeavors, a comprehensive understanding of statistical methodology is required to rigorously assess the incremental value of novel biomarkers in existing clinical risk prediction mo …

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