Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells

Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells

Yuin-Han Loh, Weiwei Zhang, Xi Chen, Joshy George, Huck-Hui Ng;Yuin-Han Loh;Weiwei Zhang;Xi Chen;Joshy George;Huck-Hui Ng;
genes & development 2007 Vol. 21 pp. 2545-
145
ng2007genesjmjd1a

Abstract

Embryonic stem (ES) cells are pluripotent cells with the ability to self-renew indefinitely. These unique properties are controlled by genetic factors and chromatin structure. The exit from the self-renewing state is accompanied by changes in epigenetic ...

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