High-fat diet disrupts behavioral and molecular circadian rhythms in mice
Abstract
The circadian clock programs daily rhythms and coordinates multiple behavioral and physiological processes, including activity, sleep, feeding, and fuel homeostasis. Recent studies indicate that genetic alteration in the core molecular clock machinery can have pronounced effects on both peripheral a …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
Inbred C57BL
animals
pubmed abstract
nih
national institutes of health
national library of medicine
behavior
research support
male
N.I.H.
Extramural
Receptors
gene expression regulation / drug effects
cytoplasmic and nuclear / metabolism
motor activity / drug effects
cytoplasmic and nuclear / physiology
feeding behavior / drug effects
dietary fats / administration & dosage
Animal / drug effects*
trans-activators / physiology
trans-activators / genetics
central nervous system / drug effects
pmid:17983587
doi:10.1016/j.cmet.2007.09.006
akira kohsaka
aaron d laposky
joseph bass
clock proteins
circadian rhythm / drug effects*
dietary fats / pharmacology*
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270607
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