A Dectin-1-Caspase-8 Pathway Licenses Canonical Caspase-1 Inflammasome Activation and Interleukin-1β Release in Response to a Pathogenic Fungus
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A Dectin-1-Caspase-8 Pathway Licenses Canonical Caspase-1 Inflammasome Activation and Interleukin-1β Release in Response to a Pathogenic Fungus

Ketelut-Carneiro, Natália;Ghosh, Sreya;Levitz, Stuart M;Fitzgerald, Katherine A;da Silva, João Santana;
The Journal of infectious diseases 2018 Vol. 217 pp. 329-339
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natália2018thea

Abstract

The fungal pathogen P brasiliensis activates caspase-8 downstream of dectin-1 recognition leading to ASC oligomerization, caspase-1 activation, and IL-1β proces

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https://doi.org/10.1093/infdis/jix568

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