Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression

Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression

Steve Lianoglou, Vidur Garg, Julie L. Yang, Christina S. Leslie, Christine Mayr;Steve Lianoglou;Vidur Garg;Julie L. Yang;Christina S. Leslie;Christine Mayr;
genes & development 2013 Vol. 27 pp. 2380-
126
mayr2013genesubiquitously

Abstract

More than half of human genes use alternative cleavage and polyadenylation (ApA) to generate mRNA transcripts that differ in the lengths of their 3′ untranslated regions (UTRs), thus altering the post-transcriptional fate of the message and likely ...

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