Determinants of amikacin first peak concentration in critically ill patients
Abstract
Amikacin antimicrobial effect has been correlated with the ratio of the peak concentration (Cmax ) to the minimum inhibitory concentration. A target Cmax ≥ 60-80 mg/L has been suggested. It has been shown that such target is not achieved in a large proportion of critically ill …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
female
male
middle aged
regression analysis
Retrospective Studies
microbial sensitivity tests
intensive care units
anti-bacterial agents / therapeutic use*
critical illness
amikacin / therapeutic use*
pmid:29660162
doi:10.1111/fcp.12374
clément boidin
sophie jenck
arnaud friggeri
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269429
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