14-3-3 mitigates alpha-synuclein aggregation and toxicity in the in vivo preformed fibril model
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14-3-3 mitigates alpha-synuclein aggregation and toxicity in the in vivo preformed fibril model

Rachel Underwood, Mary Gannon, Aneesh Pathak, Navya Kapa, Sidhanth Chandra, Alyssa Klop, Talene A. Yacoubian;Rachel Underwood;Mary Gannon;Aneesh Pathak;Navya Kapa;Sidhanth Chandra;Alyssa Klop;Talene A. Yacoubian;
acta neuropathologica communications 2021 Vol. 9 pp. -
110
yacoubian2021acta14-3-3

Abstract

Alpha-synuclein (αsyn) is the key component of proteinaceous aggregates termed Lewy Bodies that pathologically define a group of disorders known as synucleinopathies, including Parkinson’s Disease (PD) and Dementia with Lewy Bodies. αSyn ...

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DOI:
10.1186/s40478-020-01110-5
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC77921...

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