GH Knockout Mice Have Increased Subcutaneous Adipose Tissue With Decreased Fibrosis and Enhanced Insulin Sensitivity

GH Knockout Mice Have Increased Subcutaneous Adipose Tissue With Decreased Fibrosis and Enhanced Insulin Sensitivity

List, Edward O;Berryman, Darlene E;Buchman, Mathew;Jensen, Elizabeth A;Funk, Kevin;Duran-Ortiz, Silvana;Qian, Yanrong;Young, Jonathan A;Slyby, Julie;McKenna, Savannah;Kopchick, John J;
endocrinology 2019 Vol. 160 pp. 1743-1756
195
o2019endocrinologygh

Abstract

Abstract. In 1997, our laboratory used targeted gene disruption of the GH receptor (GHR) to generate GHR knockout (GHR−/−) mice, which have been used in >127

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