Surface pH buffering to promote degradation of mesoporous silica nanoparticles under a physiological condition
Abstract
Despite significant advancement of mesoporous silica nanoparticle (MSN)-based biomedical research, studies have not been done enough to understand biodegradability of functional MSNs for better clinical efficacy. Polyethyleneimine (PEI) is one of the mostly used surface functionalities of MSNs, owin …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
pubmed abstract
nih
national institutes of health
national library of medicine
nanoparticles / chemistry*
particle size
surface properties
hydrogen-ion concentration
phosphates / chemistry
buffers
porosity
silicon dioxide / chemistry*
pmid:30172772
doi:10.1016/j.jcis.2018.08.088
eunshil choi
sehoon kim
sodium chloride / chemistry
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269118
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