National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine treatment outcome research support non-u.s. gov't adult female male aged middle aged Comparative Study Prospective Studies Clinical Trial Phase III Randomized Controlled Trial Double-Blind Method Multicenter Study anti-bacterial agents / adverse effects microbial sensitivity tests feces / microbiology intention to treat analysis anti-bacterial agents / therapeutic use* anti-bacterial agents / pharmacokinetics secondary prevention enterocolitis vancomycin / adverse effects vancomycin / therapeutic use* investigators=[] affs=[]) pmid:21288078 doi:10.1056/nejmoa0910812 thomas j louie mark a miller collabauthor(name='opt-80-003 clinical study group' aminoglycosides / adverse effects aminoglycosides / pharmacokinetics aminoglycosides / therapeutic use* clostridioides difficile* / classification clostridioides difficile* / drug effects clostridioides difficile* / isolation & purification clostridium infections / drug therapy* pseudomembranous / drug therapy fidaxomicin vancomycin / pharmacokinetics