Prospective Evaluation of the Effect of an Aminoglycoside Dosing Regimen on Rates of Observed Nephrotoxicity and Ototoxicity
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Prospective Evaluation of the Effect of an Aminoglycoside Dosing Regimen on Rates of Observed Nephrotoxicity and Ototoxicity

Michael J. Rybak, Betty J. Abate, S. Lena Kang, Michael J. Ruffing, Stephen A. Lerner, George L. Drusano;Michael J. Rybak;Betty J. Abate;S. Lena Kang;Michael J. Ruffing;Stephen A. Lerner;George L. Drusano;
Antimicrobial agents and chemotherapy 1999 Vol. 43 pp. 1549-
177
drusano1999antimicrobialprospective

Abstract

The nephrotoxicity and ototoxicity associated with once-daily versus twice-daily administration of aminoglycosides was assessed in patients with suspected or proven gram-negative bacterial infections in a randomized, double-blind clinical trial. Patients ...

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