research support non-u.s. gov't Comparative Study Randomized Controlled Trial initials='g' affs=[] is_editor=false suffix=none equal_contrib=false) initials='j' initials='a' initials='h' initials='b' initials='n' author(firstnames='w' initials='w' initials='p' initials='l' initials='k' author(firstnames='j' author(firstnames='g' author(firstnames='h' author(firstnames='p' author(firstnames='l' author(firstnames='a' initials='d' initials='s' initials='m' initials='o' initials='f' initials='c' initials='i' initials='r' initials='e' initials='v' investigators=[author(firstnames='c' author(firstnames='s' author(firstnames='n' author(firstnames='c' author(firstnames='t' initials='t' author(firstnames='m' author(firstnames='d' author(firstnames='e' author(firstnames='b' author(firstnames='k' author(firstnames='r' lastname='campbell' author(firstnames='v' initials='z' lastname='chen' lastname='leblanc' pmid:25184863 doi:10.1056/nejmoa1402551 lotfi benboubker meletios a dimopoulos collabauthor(name='first trial team' lastname='forsyth' lastname='presgrave' lastname='szer' lastname='durrant' lastname='mollee' lastname='coghlan' lastname='wellwood' lastname='cannell' lastname='prince' lastname='eek' lastname='horvath' lastname='harrison' lastname='renwick' lastname='thaler' lastname='petzer' lastname='kasparu' lastname='bauernhofer' lastname='meran' lastname='fridrik' lastname='balcke' lastname='gisslinger' lastname='greil' lastname='doyen' lastname='meuleman' lastname='pierre' lastname='vekemans' lastname='demuynck' lastname='wu' lastname='van droogenbroeck' lastname='schots' author(firstnames='f' lastname='offner' lastname='van de velde' lastname='tosikyan' lastname='shustik' lastname='song' lastname='lemieux' lastname='minuk' lastname='lalancette' lastname='cheung' lastname='noble' lastname='vanderjagt' lastname='desjardins' lastname='aucoin' lastname='dueck' lastname='yee' lastname='reiman' lastname='kouroukis' lastname='assouline' lastname='al-tourah' lastname='lu' lastname='liu' author(firstnames='z' lastname='shen' lastname='alexis' lastname='audhuy' author(firstnames='i' lastname='azais' lastname='belhadj' lastname='benramdane' lastname='tempescul' lastname='boue' lastname='rose' lastname='bourhis' lastname='bouscary' lastname='caillot' lastname='casassus' lastname='de renzis' lastname='genet' lastname='de revel' lastname='dib' lastname='dorvaux' lastname='etienne' lastname='gabriel' lastname='eisenmann' author(firstnames='o' lastname='fitoussi' lastname='garderet' lastname='gaspard'