Gene expression and cell cycle arrest mediated by transcription factor DMP1 is antagonized by D-type cyclins through a cyclin-dependent-kinase-independent mechanism
Abstract
A novel 761-amino-acid transcription factor, DMP1, contains a central DNA binding domain that includes three imperfect myb repeats flanked by acidic transactivating domains at the amino and carboxyl termini. D-type cyclins associate with a region of the DMP1 DNA binding domain immediately adjacent t …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
gene expression
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
P.H.S.
cell line
3T3 Cells
Transcription Factors / metabolism*
chromosome mapping
recombinant fusion proteins / genetics
transcription factors / genetics
dna / metabolism
transcriptional activation
cell division
binding sites
recombinant fusion proteins / metabolism
cell cycle*
cyclin-dependent kinases / genetics
cyclin-dependent kinases / metabolism*
k inoue
c j sherr
pmid:9488476
pmc108874
doi:10.1128/mcb.18.3.1590
cyclin d1 / genetics
cyclin d1 / metabolism*
cyclin-dependent kinase 4
proto-oncogene proteins*
spodoptera / cytology
transcription factors / antagonists & inhibitors
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268848
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