Alzheimer’s disease brain contains tau fractions with differential prion-like activities
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Alzheimer’s disease brain contains tau fractions with differential prion-like activities

Longfei Li, Ruirui Shi, Jianlan Gu, Yunn Chyn Tung, Yan Zhou, Dingwei Zhou, Ruozhen Wu, Dandan Chu, Nana Jin, Kevin Deng, Jiawei Xu, Cheng-Xin Gong, Khalid Iqbal, Fei Liu;Longfei Li;Ruirui Shi;Jianlan Gu;Yunn Chyn Tung;Yan Zhou;Dingwei Zhou;Ruozhen Wu;Dandan Chu;Nana Jin;Kevin Deng;Jiawei Xu;Cheng-Xin Gong;Khalid Iqbal;Fei Liu;
acta neuropathologica communications 2021 Vol. 9 pp. -
87
liu2021actaalzheimer’s

Abstract

Neurofibrillary tangles (NFTs) made of abnormally hyperphosphorylated tau are a hallmark of Alzheimer’s disease (AD) and related tauopathies. Regional distribution of NFTs is associated with the progression of the disease and has been proposed ...

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DOI:
10.1186/s40478-021-01127-4
URL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC78909...

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