Nonstable Staphylococcus aureus Small-Colony Variants Are Induced by Low pH and Sensitized to Antimicrobial Therapy by Phagolysosomal Alkalinization
Leimer, Nadja;Rachmühl, Carole;Palheiros Marques, Miguel;Bahlmann, Anna Sophie;Furrer, Alexandra;Eichenseher, Fritz;Seidl, Kati;Matt, Ulrich;Loessner, Martin J.;Schuepbach, Reto A.;Zinkernagel, Annelies S.;
The Journal of infectious diseases2016Vol. 213pp. 305-313
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nadja2016thenonstable
Abstract
Abstract. Background. Staphylococcus aureus–infected patients treated with antibiotics that are effective in vitro often experience relapse of infection because