Recombinant tumor necrosis factor alpha inhibits growth of methylcholanthrene-induced sarcoma and enhances natural killer activity of tumor-infiltrating lymphocytes in aging rats
Abstract
The effect of recombinant human tumor necrosis factor alpha (rHuTNF-alpha) on the growth of immunogenic, methylcholanthrene-induced sarcoma (MC-Sa) and natural killer (NK) cell activity of tumor-infiltrating lymphocytes (TIL) in adult and aging rats was investigated. In both groups of animals the gr …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
male
Comparative Study
Rats
wistar
adjuvants
cytotoxicity
cell division / drug effects
tumor necrosis factor-alpha / pharmacology*
experimental / drug therapy*
sarcoma
experimental / chemically induced
lymphocytes
killer cells
pmid:8010877
m ziółkowska
j j nowak
a ryzewska
immunologic / pharmacology*
aging / immunology*
immunologic / drug effects
natural / drug effects*
tumor-infiltrating / drug effects*
methylcholanthrene
neoplasm transplantation
experimental / immunology*
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268564
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