Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS
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Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS

Erin R.P. Shull, Youngsoo Lee, Hironobu Nakane, Travis H. Stracker, Jingfeng Zhao, Helen R. Russell, John H.J. Petrini, Peter J. McKinnon;Erin R.P. Shull;Youngsoo Lee;Hironobu Nakane;Travis H. Stracker;Jingfeng Zhao;Helen R. Russell;John H.J. Petrini;Peter J. McKinnon;
genes & development 2009 Vol. 23 pp. 171-
99
mckinnon2009genesdifferential

Abstract

The MRN complex (Mre11/RAD50/NBS1) and ATM (ataxia telangiectasia, mutated) are critical for the cellular response to DNA damage. ATM disruption causes ataxia telangiectasia (A-T), while MRN dysfunction can lead to A-T-like disease (ATLD) or Nijmegen ...

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DOI:
10.1101/gad.1746609
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC264854...

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