The NPY Y1 receptor antagonist BIBP 3226 blocks NPY induced feeding via a non-specific mechanism
Abstract
We have previously shown that intracerebroventricular BIBP 3226 inhibits NPY induced feeding in rats. However, this was associated with abnormal behaviour, likely to be due to interaction with Y1 receptors involved in mechanisms other than the control of food intake. In order to minimise such intera …
Keywords
injections
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
male
Rats
Receptors
dose-response relationship
drug
wistar
arginine / pharmacology
arginine / analogs & derivatives*
eating / physiology
stereoisomerism
pmid:9802432
doi:10.1016/s0167-0115(98)00091-3
d g morgan
c j small
s bloom
arginine / administration & dosage
arginine / chemistry
eating / drug effects*
neuropeptide y / administration & dosage
neuropeptide y / pharmacology*
neuropeptide y / physiology
paraventricular hypothalamic nucleus / drug effects
paraventricular hypothalamic nucleus / physiology
neuropeptide y / antagonists & inhibitors*
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268390
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