Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator

Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator

Perkins ND;Felzien LK;Betts JC;Leung K;Beach DH;Nabel GJ;;
Science (New York, N.Y.) 1997 Vol. 275 pp. -
265
nd1997scienceregulation

Abstract

The nuclear factor kappaB (NF-kappaB) transcription factor is responsive to specific cytokines and stress and is often activated in association with cell damage and growth arrest in eukaryotes. NF-kappaB is a heterodimeric protein, typically composed of 50- and 65-kilodalton subunits of the Rel fami …

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