Transcription activation by the adenovirus E1a protein
Abstract
The adenovirus E1a protein stimulates transcription of a wide variety of viral and cellular genes. It is shown here that E1a has the two functions characteristic of a typical cellular activator: one direct E1a to the promoter, perhaps by interacting with a DNA-bound protein, and the other, an activa …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
genetic
pubmed abstract
nih
national institutes of health
national library of medicine
models
research support
non-u.s. gov't
u.s. gov't
P.H.S.
oncogene proteins
Genes
adenoviridae / genetics*
genetic*
Viral
DNA-Binding Proteins / physiology*
Gene Expression Regulation*
Promoter Regions
transcription
viral*
cell transformation
m r green
pmid:2521923
doi:10.1038/338039a0
j w lillie
adenovirus early proteins
viral / physiology*
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267716
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