Global analysis of growth phase responsive gene expression and regulation of antibiotic biosynthetic pathways in Streptomyces coelicolor using DNA microarrays
Jianqiang Huang, Chih-Jian Lih, Kuang-Hung Pan, Stanley N. Cohen;Jianqiang Huang;Chih-Jian Lih;Kuang-Hung Pan;Stanley N. Cohen;
genes & development2001Vol. 15pp. 3183-
178
cohen2001genesglobal
Abstract
The eubacterial species Streptomyces coelicolor proceeds through a complex growth cycle in which morphological differentiation/development is associated with a transition from primary to secondary metabolism and the production of antibiotics. We used ...