Protein disulfide isomerase ERp57 protects early muscle denervation in experimental ALS
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Protein disulfide isomerase ERp57 protects early muscle denervation in experimental ALS

Pablo Rozas, Cristina Pinto, Francisca Martínez Traub, Rodrigo Díaz, Viviana Pérez, Daniela Becerra, Patricia Ojeda, Jorge Ojeda, Madison T. Wright, Jessica Mella, Lars Plate, Juan Pablo Henríquez, Claudio Hetz, Danilo B. Medinas;Pablo Rozas;Cristina Pinto;Francisca Martínez Traub;Rodrigo Díaz;Viviana Pérez;Daniela Becerra;Patricia Ojeda;Jorge Ojeda;Madison T. Wright;Jessica Mella;Lars Plate;Juan Pablo Henríquez;Claudio Hetz;Danilo B. Medinas;
acta neuropathologica communications 2021 Vol. 9 pp. -
128
medinas2021actaprotein

Abstract

Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disease that affects motoneurons. Mutations in superoxide dismutase 1 (SOD1) have been described as a causative genetic factor for ALS. Mice overexpressing ALS-linked mutant ...

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DOI:
10.1186/s40478-020-01116-z
URL:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC78632...

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