TEX15 associates with MILI and silences transposable elements in male germ cells
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TEX15 associates with MILI and silences transposable elements in male germ cells

Fang Yang, Yemin Lan, Radha Raman Pandey, David Homolka, Shelley L. Berger, Ramesh S. Pillai, Marisa S. Bartolomei, P. Jeremy Wang;Fang Yang;Yemin Lan;Radha Raman Pandey;David Homolka;Shelley L. Berger;Ramesh S. Pillai;Marisa S. Bartolomei;P. Jeremy Wang;
genes & development 2020 Vol. 34 pp. 745-
121
wang2020genestex15

Abstract

DNA methylation is a major silencing mechanism of transposable elements (TEs). Here we report that TEX15, a testis-specific protein, is required for TE silencing. TEX15 is expressed in embryonic germ cells and functions during genome-wide epigenetic reprogramming. ...

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DOI:
10.1101/gad.335489.119
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC726314...

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