Hepatitis C Virus-Infected Patients Receiving Opioid Substitution Therapy Experience Improvement in Patient-Reported Outcomes Following Treatment With Interferon-Free Regimens
Abstract
Receiving IFN-free regimens leads to PRO improvement during treatment and after the SVR-12, regardless of OST status. HCV-infected subjects receiving OST did not experience similar PRO improvements with IFN-containing therapy, suggesting that IFN-based therapy may be less suitable for this vulnerabl …
Keywords
hepatitis c
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
treatment outcome
research support
non-u.s. gov't
adult
female
male
middle aged
drug therapy
combination
antiviral agents / therapeutic use*
ribavirin / administration & dosage
ribavirin / therapeutic use
chronic / drug therapy*
hepacivirus
sofosbuvir / therapeutic use
pmid:29293991
doi:10.1093/infdis/jix681
maria stepanova
alexander thompson
zobair m younossi
interferons / administration & dosage*
interferons / therapeutic use
opiate substitution treatment*
patient reported outcome measures*
sofosbuvir / administration & dosage
sustained virologic response
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266289
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