Machining of hybrid metal matrix composite is difficult as the particulates are abrasive in nature and they behave like a cutting edge during machining resulting in quick tool wear and induces vibration. An attempt was made in this experimental study to evaluate the machining characteristics of hybrid metal matrix composite, and a mathematical model was developed to predict the responses, namely surface finish, intensity of vibration and work-tool interface temperature for known cutting condition while machining was performed in computer numerical control lathe. Design of experiments approach was used to conduct the trials; response surface methodology was employed to formulate a mathematical model. The experimental study inferred that the vibration in V x, V y, and V z were 41.59, 45.17, and 26.45 m/s2, respectively, and surface finish R a, R q, and R z were 1.76, 3.01, and 11.94 μm, respectively, with work-tool interface temperature ‘T’ of 51.74 °C for optimal machining parameters, say, cutting speed at 175 m/min, depth of cut at 0.25 mm and feed rate at 0.1 mm/rev during machining. Experimental results were in close conformity with response surface method overlay plot for responses.