Cutting edge: stealth influenza virus replication precedes the initiation of adaptive immunity

Cutting edge: stealth influenza virus replication precedes the initiation of adaptive immunity

Moltedo B;López CB;Pazos M;Becker MI;Hermesh T;Moran TM;;
Journal of immunology (Baltimore, Md. : 1950) 2009 Vol. 183 pp. -
262
b2009journalcutting

Abstract

A timely immune response is crucial for the effective control of virus infection. The influenza virus NS1 protein interferes with the expression of key proinflammatory cytokines from infected cells in vitro. To investigate the effect of NS1 during the onset of immunity in vivo, we systematically stu …

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