Direct allylic C–H alkylation of enol silyl ethers enabled by photoredox–Brønsted base hybrid catalysis

Direct allylic C–H alkylation of enol silyl ethers enabled by photoredox–Brønsted base hybrid catalysis

Ohmatsu, Kohsuke;Nakashima, Tsubasa;Sato, Makoto;Ooi, Takashi;
Nature communications 2019 Vol. 10 pp. 1-7
328
ohmatsu2019directnature

Abstract

Allylic C–H activation of enol silyl ethers via one-electron oxidation is usually accompanied by undesired desilylation. Here, under hybrid photoredox and Brønsted base catalysis, the authors show the mild functionalization of enol silyl ethers, providing a platform to access an array of complex carbonyl compounds.

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