A general deoxygenation approach for synthesis of ketones from aromatic carboxylic acids and alkenes

A general deoxygenation approach for synthesis of ketones from aromatic carboxylic acids and alkenes

Zhang, Muliang;Xie, Jin;Zhu, Chengjian;
Nature communications 2018 Vol. 9 pp. 1-10
268
zhang2018anature

Abstract

Synthesis of aryl ketones can be generally achieved via C–C coupling strategies. Here, the authors show a deoxygenative coupling of carboxylic acids and alkenes enabled by photoredox catalysis and report a wide scope of products, including bioactive and macrocyclic ketones.

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