Botulinum toxin: chemistry, pharmacology, toxicity, and immunology
Brin MF;;
Muscle & nerve. Supplement1997Vol. 6pp. -
131
mf1997musclebotulinum
Abstract
The seven serotypes of botulinum toxin (BTX) produced by Clostridium botulinum exert their paralytic effect by inhibiting acetylcholine release at the neuromuscular junction. Each of these zinc endopeptidases cleaves one or more proteins involved in vesicle transport and membrane fusion. The extent …