Fluoride exposure during pregnancy and lactation triggers oxidative stress and molecular changes in hippocampus of offspring rats

Fluoride exposure during pregnancy and lactation triggers oxidative stress and molecular changes in hippocampus of offspring rats

Ferreira MKM;Aragão WAB;Bittencourt LO;Puty B;Dionizio A;Souza MPC;Buzalaf MAR;de Oliveira EH;Crespo-Lopez ME;Lima RR;;
Ecotoxicology and environmental safety 2020 Vol. 208 pp. -
185
mkm2020ecotoxicologyfluoride

Abstract

Long-term exposure to high concentrations of fluoride (F) can damage mineralized and soft tissues such as bones, liver, kidney, intestine, and nervous system of adult rats. The high permeability of the blood-brain barrier and placenta to F during pregnancy and lactation may be critical to neurologic …

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