Mesoporous silicas have enjoyed great interest among scientists practically from the moment of their discovery thanks to their unique attractive properties. Many types of mesoporous silicas have been described in literature, the most thoroughly MCM-41 and SBA-15 ones. The focus of this review are the methods of syntheses, characterization and use of mesoporous silicas from SBA (Santa Barbara Amorphous) and HMM (Hybrid Mesoporous Materials) groups. The first group is represented by (i) SBA-1 of three-dimensional cubic structure and Pm3¯n symmetry and (ii) SBA-2 of three-dimensional combined hexagonal and cubic structures and P63/mmc symmetry. The HMM group is represented by (i) HMM-1 of two-dimensional hexagonal structure and p6mm symmetry and (ii) HMM-2 of three-dimensional structure and P63/mmc symmetry. The paper provides comprehensive information on the above-mentioned silica materials available so far, also including the data for the silicas modified with metal ions or/and organic functional groups and examples of the materials applications.