The metasedimentary sequence of the Cushamen Formation in the western North Patagonian Massif is 540 m thick and comprises six sedimentary lithofacies associations related to a glacimarine environment. Four of these lithofacies represent distal glacimarine environments, whereas another one was deposited in proximal glacimarine environments, and the last includes subglacial environments. The organization and configuration of these lithofacies associations represent the advance and retreat of the glacier masses. The maximum glacial advance is correlatable with the G2 glacial interval of the Pennsylvanian Pampa de Tepuel, Las Salinas and Valley Chico, formations of the Extraandean Chubut, and the southern part of Neuquén Cordillera. Contemporaneously, in southern Chile there are marine and glacimarine sediments. The chronostratigraphic relationships between the Silurian to Permian units allow five paleogeographic stages to be distinguished. The middle Silurian–late Devonian igneous rocks represent the first magmatic stage. The second stage, which is transitional to the first, is represented by a marine basin that includes the late Devonian–early Carboniferous Esquel and Río Pescado formations and the Llanquihue Complex. The third stage (early–late Carboniferous) includes granitoids of the second magmatic event that partially overlapped the first magmatic igneous belt. The fourth stage belongs to the late Carboniferous sedimentation of the Cushamen and equivalent formations. The extended early Permian magmatism was the last Paleozoic event in the studied area.