Natural gas is becoming more and more a commodity in the global energy consumption. New technologies like the conversion from gas to liquid, contribute to this. But more than 16 % of the currently known global gas reserves cannot be produced due to severe CO2 and/or H2S contamination: (CO2 > 10% and H2S> 5%). The traditional technology of amine treatment is not able to economically remove these contaminants. The objective of this article is to investigate the possibilities of centrifugal separation to resolve the problem. After analyzing the existing situation, in the centrifugal separation of natural gas, some innovations in separators design and theory are suggested. The aim of the presented theoretical considerations is that the complex theory of separation to adapt to the needs of engineers engaged on the design, development and operation of these devices. [Projekat Ministarstva nauke Republike Srbije, br. 33001]