ionic liquid-mediated, rapid n-alkylation of heterocyclic compounds with trialkyl phosphites in the presence of dialkyl acetylenedicarboxylates
;Alireza Hassanabadi;Mohammad H. Mosslemin;Mohammad Anary-Abbasinejad;Azadeh Kalantarinejad;Mozhdeh Jerjisi Shirazi
Journal of pharmaceutical and biomedical analysis2012Vol. 9pp. 2074-2078
234
hassanabadi2012e-journalionic
Abstract
Ionic liquids such as 1,3-dialkylimidazolium bromides and make excellent solvents for N-alkylation of heterocyclic compounds such as saccharin and rhodanine with trialkyl phosphites in the presence of dialkyl acetylenedicarboxylates.