an efficient protocol for the solid-phase synthesis of malondiamides
;Andreas L. Marzinzik;Markus M. Vögtle
Journal of ethnopharmacology2005Vol. 10pp. 1438-1445
120
marzinzik2005moleculesan
Abstract
A novel and straightforward solid-phase synthesis of malondiamides containing a free nitrogen has been developed. These intermediates, which can be directly obtained in good yield and purity, can be further derivatised. This approach can be used for the synthesis of large split-and-mix-libraries.